Can Caffeine Withdrawal Cause Profound Body Aches and Lethargy?
1. Introduction Yes, discontinuing caffeine can cause profound body aches and profound lethargy due to the sudden unmasking of upregulated adenosine receptors and a sharp, rebound increase in cranial and systemic blood flow. Caffeine is the most widely consumed psychoactive substance globally, functioning primarily as an antagonist to adenosine, a neurotransmitter that promotes sleep and … Read more