Why do my calf muscles twitch rhythmically while sitting at my desk?

Why do my calf muscles twitch rhythmically while sitting at my desk?

1. Introduction Rhythmic twitching in the calf muscles while sitting is typically caused by benign fasciculations, which occur when localized motor nerve endings spontaneously misfire. Prolonged sitting compresses the vascular and neurological pathways in the legs, and when combined with fatigue, caffeine consumption, or mild electrolyte imbalances, these peripheral nerves become hyper-excitable, leading to visible, … Read more