Why Do My Armpits Turn Dark and Velvety Out of Nowhere?

Why Do My Armpits Turn Dark and Velvety Out of Nowhere?

1. Introduction The sudden appearance of dark, velvety skin in the armpits is a clinical sign known as acanthosis nigricans, which serves as a powerful dermatological marker for systemic metabolic dysfunction. This hyperpigmentation and thickening of the skin is most frequently driven by severe insulin resistance, where excess circulating insulin inappropriately stimulates epidermal skin cells … Read more