Dedifferentiated Carcinoma: Molecular Mechanisms, Histopathology, and Clinical Treatment
1. Introduction to Dedifferentiated Carcinoma Dedifferentiated carcinoma is a unique and aggressive pathological entity defined by a distinct, abrupt morphological transition within a single tumor. It is characterized by the presence of a low-grade, well-differentiated carcinoma that sits immediately adjacent to, and sharply transitions into, a high-grade, undifferentiated malignant component. This dual-component nature creates immense … Read more