Diabetic Ischemic Foot Ulcer: Pathophysiology, Risks, and Management
1. Introduction A diabetic ischemic foot ulcer is a complex, limb-threatening complication arising from the intersection of prolonged metabolic dysfunction and severe vascular disease. Diabetes mellitus induces systemic changes that simultaneously destroy sensory nerves and rapidly accelerate the hardening of peripheral arteries. When structural blockages prevent oxygenated blood from reaching the extremities, the fragile, desensitized … Read more