Diabetic Gangrene: Pathophysiology, Clinical Assessment, and Management

Diabetic Gangrene: Pathophysiology, Clinical Assessment, and Management

1. Introduction Gangrene secondary to diabetes mellitus represents a profound and complex complication of chronic metabolic dysregulation. It is characterized by the irreversible death of tissue, most frequently occurring in the distal extremities such as the toes and feet. Diabetes creates a uniquely destructive environment within the body by simultaneously damaging the peripheral nervous system … Read more