What causes severe cramping on the first day of menstruation?
1. Introduction and Direct Answer Severe cramping on the first day of menstruation, clinically termed primary dysmenorrhea, is caused by the localized overproduction of prostaglandins within the endometrial lining, which induces strong, ischemic contractions of the uterine muscle. Secondary dysmenorrhea must also be considered, wherein underlying structural pathologies such as endometriosis, uterine fibroids, or adenomyosis … Read more