Open Iniencephaly: Pathophysiology, Prenatal Diagnosis, and Prognosis
1. Introduction Open iniencephaly is a catastrophic, universally lethal congenital malformation classified within the spectrum of severe neural tube defects. It is characterized by an extreme, fixed retroflexion of the fetal head, profound spinal deformities, and an extensive defect in the occipital bone and cervical vertebrae. The designation “open” indicates the absence of intact skin … Read more