What causes the eyelids to swell overnight and become puffy?
1. Introduction Eyelids swell overnight and become puffy primarily due to localized fluid retention, a condition clinically termed periorbital edema, which is strongly exacerbated by the supine sleeping position. During sleep, gravity ceases to pull interstitial fluid downward toward the lower extremities, allowing it to pool in the highly distensible, loose connective tissue surrounding the … Read more