Comedocarcinoma (NOS): High-Grade Pathology, Radiological Signs, and Surgical Management
1. Introduction to Comedocarcinoma Comedocarcinoma, not otherwise specified (NOS), represents a distinct, biologically aggressive subtype of non-invasive breast malignancy. It is a highly specific variant of ductal carcinoma in situ characterized by the rapid proliferation of high-grade, abnormal epithelial cells strictly confined within the milk ducts. The clinical hallmark of this disease is central cellular … Read more