Why do I get a raised thick keloid scar from a tiny minor surface scratch?

Why do I get a raised thick keloid scar from a tiny minor surface scratch?

1. Introduction A raised thick keloid scar forms from a minor surface scratch due to a genetic dysregulation in the wound healing process that causes fibroblasts to aggressively overproduce collagen. Instead of halting collagen deposition once the microscopic wound is closed, the cellular signaling pathway malfunctions, resulting in continuous scar tissue growth that expands well … Read more

Keloid Scars: Causes, Cellular Mechanisms, and Dermatological Management

Keloid Scars: Causes, Cellular Mechanisms, and Dermatological Management

1. Introduction A keloid scar is a benign, fibroproliferative tumor of the skin characterized by the relentless and unregulated accumulation of dense collagen fibers. Following a physical injury to the dermal layers, the body initiates a cascade of cellular events designed to repair the defect. In susceptible individuals, this reparative mechanism loses its biological brakes, … Read more