Why Do My Knees Feel Weak and Wobbly After Completing a Long Run?

Why Do My Knees Feel Weak and Wobbly After Completing a Long Run?

1. Introduction Experiencing weak and wobbly knees after completing a long run is primarily the result of profound neuromuscular fatigue and acute glycogen depletion within the quadriceps muscles. During extended cardiovascular effort, the motor neurons that command the leg muscles exhaust their chemical neurotransmitters, leading to inefficient muscle contractions and a loss of joint stability. … Read more