What causes sudden swelling in the left leg and ankle?

What causes sudden swelling in the left leg and ankle?

1. Introduction and Direct Answer Sudden swelling localized specifically to the left leg and ankle is a significant clinical presentation most commonly caused by deep vein thrombosis, a potentially dangerous blood clot obstructing venous return. In the left leg, this vascular occlusion is uniquely exacerbated by May-Thurner syndrome, an anatomical variant where the right iliac … Read more