Injection Site Urticaria: Immunological Mechanisms and Clinical Management

Injection Site Urticaria: Immunological Mechanisms and Clinical Management

1. Introduction Injection site urticaria is an acute, localized cutaneous reaction characterized by the rapid eruption of well-circumscribed, raised, erythematous wheals at the location of a recent medical puncture. Commonly referred to as hives, this localized swelling is the visible manifestation of intense vascular permeability driven by the sudden release of inflammatory mediators from resident … Read more