Methadone Misuse: Pharmacology, Health Risks, and Clinical Management
1. Introduction to Methadone Pharmacology Methadone is a potent, long-acting synthetic opioid agonist utilized globally for the management of severe chronic pain and as a foundational medication in the treatment of opioid use disorder. Unlike short-acting opioids such as heroin or oxycodone, methadone is characterized by its extended half-life and unique pharmacokinetic profile. When administered … Read more