Can stopping caffeine cold turkey cause a severe migraine?
1. Introduction Stopping caffeine abruptly precipitates severe migraines due to a rapid rebound dilation of cerebral blood vessels. Caffeine acts as a daily vasoconstrictor, narrowing the blood vessels within the brain and suppressing specific neurotransmitter receptors. Sudden cessation forces these cerebral vessels to expand forcefully, resulting in an intense rush of blood flow that violently … Read more