General Paresis in Neurosyphilis: Causes, Symptoms, and Treatment
1. Introduction General paresis, historically referred to as general paralysis of the insane or dementia paralytica, is a severe neuropsychiatric disorder representing a late-stage manifestation of neurosyphilis. This condition arises when the Treponema pallidum bacterium, the causative agent of syphilis, directly invades the brain parenchyma, leading to chronic meningoencephalitis and progressive neuronal destruction. If the … Read more