Nocturnal Cough and Wheeze: Pathophysiology and Clinical Management

Nocturnal Cough and Wheeze: Pathophysiology and Clinical Management

1. Introduction: Analyzing Respiratory Sounds The clinical presentation of nocturnal cough accompanied by a wheeze represents a specific pattern of respiratory distress that requires precise medical evaluation. A cough is a forced expulsive maneuver to clear the airway, while a wheeze is a continuous, high-pitched, musical adventitious lung sound produced when air is forced through … Read more

What causes asthma symptoms to worsen at night?

What causes asthma symptoms to worsen at night?

1. Introduction Asthma symptoms worsening at night, clinically referred to as nocturnal asthma, are primarily driven by the body’s natural circadian rhythm, which induces a drop in circulating cortisol and epinephrine while increasing parasympathetic vagal tone. These synchronized physiological changes naturally constrict the bronchial airways and promote mucosal inflammation during sleep. When this baseline nocturnal … Read more