P1-Negative Phenotype: Immunohematology and Pretransfusion Testing

P1-Negative Phenotype: Immunohematology and Pretransfusion Testing

1. Introduction The P1-negative phenotype, universally recognized in immunohematology as the P2 phenotype, designates an individual whose red blood cells completely lack the P1 glycosphingolipid antigen while maintaining normal expression of the P and Pk antigens. This phenotypic profile is a standard biological variant present in approximately a quarter of the Caucasian population. In the … Read more