P1k Phenotype: Rare Blood Group Genetics and Transfusion Medicine
1. Introduction The P1k phenotype represents an extraordinarily rare and clinically perilous condition within the architecture of human blood groups. Individuals with this phenotype exhibit a unique serological profile: their red blood cells abundantly express the P1 and Pk glycosphingolipid antigens, but fundamentally lack the P antigen (globotetraosylceramide). Because the immune system is intolerant to … Read more