Why do my palms suddenly get intensely itchy for no apparent reason?
1. Introduction Sudden, intense itching of the palms without a visible rash is typically caused by localized nerve irritation, early stages of dyshidrotic eczema, or systemic conditions such as liver dysfunction. The dense concentration of sensory nerve endings in the palms makes this area uniquely sensitive to internal biochemical shifts, triggering an acute pruritic response. … Read more