Physical Precocity: Endocrine Mechanisms, Diagnosis, and Clinical Care
1. Introduction to Early Maturation Physical precocity, known formally in pediatric endocrinology as precocious puberty, is defined as the onset of secondary sexual characteristics at an abnormally early age. Clinically, this threshold is traditionally established as the appearance of breast development in girls before the age of eight, and the onset of testicular enlargement in … Read more