Primary Physiologic Amenorrhea: Endocrine Mechanisms and Clinical Evaluation
1. Introduction to Physiologic Amenorrhea Primary physiologic amenorrhea refers to the expected absence of menstruation in young females before the typical age of menarche or due to normal, non pathological variations in developmental timing. This condition is a natural phase of maturation governed by the gradual activation of the hypothalamic pituitary ovarian axis. Clinical evaluation … Read more