Pleomorphic Lobular Carcinoma: Cellular Characteristics, Diagnosis, and Treatment Protocols

Pleomorphic Lobular Carcinoma: Cellular Characteristics, Diagnosis, and Treatment Protocols

1. Introduction Pleomorphic lobular carcinoma is a rare and aggressive variant of invasive lobular carcinoma of the breast. This distinct histological subtype retains the characteristic discohesive, single-file cellular growth pattern of classic lobular cancer but features neoplastic cells that are significantly larger, more irregular, and rapidly dividing. The diagnosis signals a more challenging clinical trajectory … Read more