Non-Allergic Hypersensitivity Disposition: Pseudoallergy Mechanisms and Management

Non-Allergic Hypersensitivity Disposition: Pseudoallergy Mechanisms and Management

1. Introduction: Understanding Hypersensitivity Reactions Non-allergic hypersensitivity disposition encompasses a spectrum of severe, often unpredictable adverse reactions that clinically mimic traditional allergies but lack the specific immunological mechanisms that define a true allergic response. Historically termed “pseudoallergy” or “anaphylactoid reactions,” these events are characterized by the rapid, massive release of inflammatory mediators from mast cells … Read more