Lutheran Negative Phenotype: The Rare Lu(a-b-) Null Blood Group

Lutheran Negative Phenotype: The Rare Lu(a-b-) Null Blood Group

1. Introduction The Lutheran negative phenotype, formally designated in immunohematology as the Lu(a-b-) or Lutheran null phenotype, represents the absolute rarest genetic classification within the Lutheran blood group system. The bottom line is that individuals possessing the true recessive form of this phenotype face extreme, life-threatening immunological risks if they require a blood transfusion, as … Read more

Lua-Positive Phenotype: Clinical Significance in Transfusion Medicine

Lua-Positive Phenotype: Clinical Significance in Transfusion Medicine

1. Introduction The Lua-positive phenotype refers to a specific genetic and serological profile within the Lutheran blood group system characterized by the physical presence of the Lua antigen on the surface of human red blood cells. The bottom line is that while possessing the Lua antigen has no negative impact on a person’s physiological health, … Read more