What Causes a Sudden Severe Migraine Immediately After Drinking One Glass of Red Wine?

What Causes a Sudden Severe Migraine Immediately After Drinking One Glass of Red Wine?

1. Introduction A sudden, severe migraine immediately after drinking one glass of red wine is typically triggered by a localized hypersensitivity to specific biochemical compounds, predominantly histamines, tyramine, and phenolic flavonoids. These organic compounds bypass the digestive defenses in susceptible individuals and enter the systemic circulation, provoking rapid vasodilation and an intense neuro-inflammatory response within … Read more