Siklos (Hydroxyurea): Uses, Side Effects & Interactions
Siklos contains hydroxyurea, a potent antimetabolite utilized extensively to reduce the frequency of painful crises in pediatric and adult patients with sickle cell anemia. The most critical side effect is profound, life-threatening myelosuppression, specifically severe neutropenia, alongside a high risk of cutaneous toxicity and significant teratogenic hazards to developing fetuses. 1. Introduction And Mechanism Of … Read more