Itvisma (Onasemnogene Abeparvovec): Uses, Side Effects & Interactions

Itvisma (Onasemnogene Abeparvovec): Uses, Side Effects & Interactions

Itvisma represents a highly advanced, single-dose intravenous gene replacement therapy utilizing Onasemnogene Abeparvovec to combat spinal muscular atrophy in infants. The most severe side effects include acute hepatotoxicity and sudden drops in blood platelets, which require meticulous clinical monitoring and aggressive systemic corticosteroid management. Strict compliance with pre-infusion testing and post-infusion immune suppression is mandatory … Read more