Type 1 Diabetes and Gangrene Risk: Mechanisms, Diagnosis, and Treatment

Type 1 Diabetes and Gangrene Risk: Mechanisms, Diagnosis, and Treatment

1. Introduction Gangrene represents the catastrophic end-stage of critical tissue ischemia, characterized by the irreversible necrosis of biological structures. When this condition arises as a complication of Type 1 Diabetes Mellitus, it reflects the severe, cumulative toll of lifelong autoimmune metabolic disruption. Unlike other forms of diabetes, Type 1 is characterized by an absolute deficiency … Read more