Metastatic Carcinoma Not Otherwise Specified: Diagnosis and Management
1. Introduction The diagnosis of metastatic carcinoma, not otherwise specified, frequently referred to in clinical oncology as Cancer of Unknown Primary, represents a profoundly complex diagnostic and therapeutic challenge. This classification indicates that a patient presents with biopsy-proven metastatic carcinoma—malignant epithelial cells that have spread to secondary anatomical sites—yet comprehensive clinical, radiological, and pathological investigations … Read more