Injection Site Extravasation: Pathophysiology and Tissue Necrosis
1. Introduction Injection site extravasation is a severe clinical complication defined as the inadvertent leakage of a vesicant or highly irritant pharmaceutical agent from its intended vascular pathway into the surrounding subcutaneous tissue. While this term is most frequently associated with intravenous infusions, it equally applies to the misplaced deposition of toxic agents during deep … Read more