Why do my knuckles get dark pigmented spots exclusively during the dry winter months?
1. Introduction Dark pigmented spots on the knuckles during the dry winter months are primarily the result of post-inflammatory hyperpigmentation triggered by severe epidermal dehydration and repetitive mechanical friction. Cold, dry air rapidly depletes the skin of its natural lipid barrier, causing microscopic cracks and irritation in the areas subjected to constant movement and stretching, … Read more