What causes a sudden charley horse in the calf while sleeping?
1. Introduction A sudden charley horse in the calf while sleeping is primarily caused by an involuntary, sustained spasm of the gastrocnemius or soleus muscles. This nocturnal cramping frequently results from a combination of muscle fatigue, localized cellular dehydration, and electrolyte imbalances that lower the firing threshold of peripheral motor nerves. When these nerves become … Read more