Holoanencephaly: Causes, Diagnosis, and Fetal Prognosis
1. Introduction to Holoanencephaly Holoanencephaly is a severe, profound congenital anomaly of the central nervous system. It represents the most extensive and clinically devastating form of anencephaly, a condition categorized broadly under neural tube defects. In this profound developmental failure, the embryonic neural tube fails to close completely at its cranial end, leading to the … Read more